genetics and genomics

JoAnne Engebrecht

JoAnne Engebrecht

  • Professor
  • Department of Molecular and Cellular Biology
  • College of Biological Sciences
JoAnne Engebrecht investigates molecular mechanisms underlying germline biology. Germ cells are essential for the propagation of all sexually reproducing organisms.  Germline stem cell divisions, meiotic differentiation and gametogenesis must be tightly coupled to ensure the formation of viable progeny; perturbations result in infertility, inviability and birth defects.
Elva Diaz

Elva Diaz

  • Professor
  • Department of Pharmacology
  • School of Medicine
Elva Diaz studies molecular mechanisms of brain development, function and disease in rodent model systems. We used expression profiling as a tool to identify genes that are developmentally regulated during mouse brain development. Candidate genes are characterized with molecular and cellular techniques and transgenic mice. Currently, we have focused our efforts on molecules that function at excitatory synapses in the hippocampus, an area of the brain important for learning and memory.
Fred Chedin

Frédéric Chédin

  • Professor
  • Department of Molecular and Cellular Biology
  • College of Biological Sciences
Frédéric Chédin studies how mammalian cells regulate gene expression programs through the formation of unusual DNA structures during transcription. The Chédin lab uses biochemical, molecular genetics, and cell culture approaches, with a focus on high-throughput genomics methods backed by computational analyses.
Sean Burgess

Sean M. Burgess

  • Professor
  • Department of Molecular and Cellular Biology
  • College of Biological Sciences
Sean Burgess explores the dynamic chromosome events that occur during the process of meiosis and how these processes are integrated to achieve accurate chromosome segregation. Chromosome missegregation is one of the leading causes of birth defects in humans. The Burgess lab combines the use of a wide array of tools, including genetics, molecular biology, biochemistry and live-cell imaging using budding yeast Saccharomyces cerevisiae and zebrafish Danio rerio as model systems.
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