Julie Bossuyt studies the molecular mechanisms that drive activation and function of the related kinases, protein kinase D and calmodulin dependent protein kinase in healthy and failing hearts. Her lab focuses on understanding the local regulatory mechanisms that control the myriad cellular outcomes for these multifunctional kinases. Tools in the lab include cutting-edge high resolution fluorescence imaging techniques (such as FRET, TIRF, FRAP and confocal) and novel biosensors to obtain unique insight into the spatiotemporal dynamics of signaling in cardiac cells.